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- ed may be caused by underlying vascular disease. if you have vascual disease and have not spoken to your gp about your ed, we would recommend you do.fatal reaction: there can be a fatal reaction between ed tablets and nitrate medications such as gtn spray. you must not take or purchase ed medication from us if you take nicorandil, a gtn spray, tablets, patch, gel or cream or any nitrate tablets (usually for heart conditions).
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